Molecular layer

Metabolomics

Metabolic signatures interpreted in the context of phenotype, treatment and inflammatory biology.

Metabolic phenotyping

Map the metabolic state of disease.

Metabolomics captures biochemical changes that emerge from disease, treatment, organ function and the surrounding microenvironment. We use targeted and discovery-driven approaches to identify signatures worth testing rather than treating feature lists as conclusions.

Discovery

Untargeted profiling

Broad molecular surveys to identify metabolic features associated with clinically defined states.

Quantification

Targeted analysis

Focused measurement of pathways and metabolites selected from biological hypotheses or discovery data.

Biofluids

Clinically relevant matrices

Plasma and other patient-derived biospecimens chosen around the biological process of interest.

Translation

From pattern to biomarker

Prioritizing reproducible features that remain interpretable in the context of clinical phenotype.